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Additionally, variations in dosing equivalence, species-specific GLP-1 receptor expression, and metabolic responsiveness further complicate the direct translation of these findings to human diseases (De Giorgi et al., 2025)
Two peptides
Weeks 8-12 : More significant improvements in deeper wrinkles, continued collagen density increase, improved skin thickness (measured via ultrasound in clinical settings), and sustained reduction in age-related skin laxity
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