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There is also evidence that moderate exercise at least five times per week for a total of 150 min per week or an increase in activity level by more than 60 min per week improved liver enzymes and other metabolic indices

++, significant improvement in predefined outcome judged by gold-standard method

The biological functions of stromal cell-derived factors 1 and 1 (SDF-1 and SDF- 1, CXCL12), macrophage-derived chemokine (MDC, CCL22), interferon-inducible T cell -chemoattractant (ITAC, CXCL11), inflammatory protein-10 (IP10, CXCL10), monokine-induced by gamma interferon (MIG, CXCL9), eotaxin (CCL11), granulocyte chemotactic protein 2 (GCP2, CXCL6), and Gro (CXCL2) have been shown to be substrates for proteolytic modification by DPP4

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