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That chain is too many steps removed from reality to hold up clinically
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To further distinguish heterogeneous conformations observed in the datasets of CTR:Cagri/CagriBB, the authentic particles of complexes were separated into multiple clusters by 3D Classification in cryoSPARC with approximately 50100k particles for each cluster
Reconstituted vials add another problem: every puncture of the septum creates an opportunity for contamination if technique is sloppy
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