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Here's what you need to know about the side effects of taking vitamin B12 supplements and whether it is possible to take too much

doi: 10.1016/j.virs.2023.12.004 68 ZhuS.Viejo-BorbollaA

An RCT of 174 patients with severe alcoholic hepatitis found that the combination of prednisolone + NAC (IV for 5 days, then oral for 2 weeks) significantly reduced 1-month mortality compared to prednisolone alone (8% vs 24%, p=0.006), though the difference was not significant at 6 months (Nguyen-Khac et al., N Engl J Med, 2011) [36]

These genetic observations suggest that blocking the function of ANGPTL3 may be useful in treating hypertriglyceridemias