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A severely degenerated rotator cuff in a 65-year-old with decades of wear will not become a healthy 25-year-old tendon
These limitations do not invalidate preclinical findings but emphasize the need for human clinical trials with appropriate sample sizes, standardized protocols, and validated outcome measures before establishing clinical efficacy in human patients
Where It Acts The primary target cells are dermal fibroblasts (the cells responsible for producing collagen, elastin, and the extracellular matrix proteins that give skin its mechanical structure) and basal keratinocytes (the proliferating cell population at the bottom of the epidermis)
**Asthma Symptoms**: Although rare, some people with asthma may experience an exacerbation of their symptoms when using glutathione supplements
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