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Activation involves signaling pathways such as JAKSTAT, NF-B, mitogen-activated protein kinase (MAPK) and calcineurin, leading to cytoskeletal changes marked by the upregulation of GFAP, vimentin and nestin 35,44,45
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The combination according to the present invention can be prepared by mixing the active ingredients with suitable excipients for the formulation of pharmaceutical and/ or dietetic compositions which can be administered to human subjects or to animals
And it acts on appetite centers in the brain, reducing hunger and promoting satiety
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