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Investigations assess its potential effects on cuprizone-associated demyelination, traumatic brain injury, neurotoxin-induced dopaminergic disruption, neurotransmitter regulation, and peripheral or central nerve regeneration
Besides, lycopene might be regarded as a potent alternative strategy for managing OLP when steroids is not appropriate, offering comparative and safer therapeutic effect with less side effects
Phase 2 trial (Lancet 2021) tested cagrilintide 0.3 mg through 4.5 mg/week as monotherapy and reported a clear dose-response, with 10.8% mean weight loss at 4.5 mg/week at 26 weeks
The outcome is that GPX4 reduces the accumulation of ROS and acts against complex lipid peroxidation to reduce cell death [27, 28]
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