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Reddys and Gland Pharma aim to widen affordability post-2031 patent expiries
Despite the fact that both GIP and GLP-1 levels depend on renal metabolism, and are increased in individuals with CKD and renal failure [45, 46], no relevant effects of eGFR on drug exposure were detected when assessing the pharmacokinetics of tirzepatide 5 mg in individuals with preserved renal function or various degrees of renal impairment [47]
[33] Another study highlighted in a large review found that people using GLP-1 medicines had a 23%31% lower chance of developing dementia than those on other diabetes drugs, specifically sulfonylureas and DPP-4 inhibitors
Body composition: Some studies have reported slight reductions in fat mass, though results remain inconsistent across different populations
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