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Important safety questions include product purity, dose accuracy, drug interactions, liver and kidney considerations, blood sugar changes, cardiovascular risk, pregnancy or breastfeeding status, and long-term exposure
The strongest support comes from clinical evidence focused on treating vitamin B12 deficiency, not from general wellness claims What science supports The NIH Fact Sheet for Health Professionals shows that intramuscular B12 injections are effective at raising blood B12 levels and correcting deficiency
However, therapeutic doses used to treat deficiency are considerably higher
With 100 mg nicotinamide administered, levels in milk would likely rise further
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