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The cysteinyl sulfur of glutathione (GSH) is maintained in the reduced state by NADPH produced in the oxidative phase of the pentose phosphate shunt and provides a nucleophilic thiol important for the detoxification of electrophilic metabolites and metabolically-produced oxidizing agents
It enhances the production of growth factors that aid in tissue regeneration, reduces inflammation, and protects against the harmful effects of oxidative stress
The largest solvent cluster is at the dimer interface and contains 104 interconnected solvent molecules, part of which are organized in a warped sheet-like structure
Medical and Editorial Review This final article has been reviewed for medical context, evidence presentation, patient safety language and editorial clarity by the multidisciplinary panel below
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