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Methods We conducted a retrospective analysis of human exposures to GLP-1 RAs reported to the National Poison Data System (NPDS) from January 1, 2012 through December 31, 2023
It works by helping your body make more insulin when your blood sugar is high
Here, we demonstrate that a peptideantibody conjugate that blocks GIPR while simultaneously activating GLP-1R (GIPR-Ab/GLP-1) requires both CNS GIPR and CNS GLP-1R for maximal weight loss in obese, primarily male, mice
Those taking concurrent GLP-1 medications or insulin should work with their healthcare team to adjust dosing and monitoring protocols, as additive effects may require close glycemic surveillance
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