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Gastrointestinal effects dominate: nausea (1722%), diarrhea (1316%), vomiting (610%), decreased appetite (79%), and indigestion (~7%)

Food & Drug Administration (FDA) has not approved glutathione for skin-whitening purposes.[4] While glutathione is widely studied for its antioxidant properties, its use for cosmetic skin lightening is considered off-label

doi:10.1002/cjoc.201300061 ZhouW, Shultz JW, Murphy N, Hawkins EM, Bernad L, Good T, Moothart L, Frackman S, Klaubert DH, Bulleit RF, Wood KV (2006) Electrophilic aromatic substituted luciferins as bioluminescent probes for glutathione S-transferase assays

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