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the 1 mg arm is the lowest measured human pharmacologic activity: Frias Lancet 2018

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Vitamin B12 injections may not be suitable for people who have a history of: allergic reaction or sensitivity to cobalt or vitamin B12 Leber disease kidney disease or impaired kidney function Also, vitamin B12 injections may not be necessary for people without a deficiency

Unlike full-length growth hormone, AOD9604 does not directly activate the growth hormone receptor but is studied as a discrete molecular fragment with distinct biological activity in experimental systems