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In addition, its importance is supported by experiments showing that inhibitors of the enzyme that recycles glutathione cause a marked increase in dehydroascorbic acid, and that dehydroascorbic acid can cause loss of transparency in the lens in animals if it is not converted back into vitamin C (Giblin 2000
doi: 10.1093/ije/18.1.45 80 JonklaasJDanielsenMWangH
Yao et al., 2023
The takeaway is that glutathione biology is well understood, while the clinical picture for supplementation is still developing
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