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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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188,208 Although a modest reduction in lean mass was observed at 12 months, muscle function, assessed via handgrip strength, improved significantly, the prevalence of sarcopenic obesity declined, and resting energy expenditure relative to lean mass increasedindicating enhanced metabolic efficiency

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Some people also experience constipation or diarrhoea at the same time, which can further disrupt normal digestion and increase gas

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