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Complementary findings in dietary obesity models have also been reported, where AgRP levels were elevated under hyperphagic conditions and reduced with food restriction, while -MSH and POMC concentrations remained unchanged [60]
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In brain and other nerve tissues, this acetyl group export by acetyl-L-carnitine out of the mitochondria into the cytosol is important in maintaining normal levels of acetyl groups for the production of acetylcholine and other acetylated neurotransmitters that are so crucial for normal brain andnerve function
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