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Ghrelin Antagonists: These peptides block the action of ghrelin, ultimately helping to decrease appetite and promote weight loss
NMR Structural Resolution of FOXO4-DRI/p53TAD2 Complex (Nature Communications, 2025) Disordered-to-Ordered Complex Formation: Structural Basis of FOXO4-DRIs Senolytic Mechanism A landmark structural study published in Nature Communications (2025) resolved the solution NMR structural models of the p53 transactivation domain (TAD2) in complex with the FOXO4 forkhead domain and with FOXO4-DRI
doi: 10.1074/jbc.275.4.2505 66 SeaverL
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