When we evaluated FcRn-mediated recycling in a cell-based assay, where the receptor is embedded in the membrane, the WT fusion was recycled 1.8-fold less efficiently than unfused WT albumin, which is in line with its shorter plasma half-life
Antioxidants may have special roles in the gastrointestinal tract, and many lifestyle features known to promote health (especially diet, exercise and the control of blood glucose and cholesterol levels) may be acting, at least in part, by antioxidant mechanisms
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PC-12 Adh cells, with neuronal properties and high glucocorticoid receptor levels, are ideal for studying stress-related neuronal responses 78,79