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For example, according to a recent review by researchers in the US looking at peptides often marketed to patients with musculoskeletal injuries, BPC-157 demonstrated potential benefits in tendon and muscle repair, but these findings are largely unvalidated in human trials, with no randomised control trials in humans relating to such uses, and the only case series having serious flaws
Newer formulations are emerging, including oral semaglutide drops and oral tirzepatide , but the injectable versions remain the standard for weight management
Vision Loss and NAION Concerns Non-arteritic anterior ischemic optic neuropathy (NAION) has emerged as a particularly devastating injury linked to GLP-1 medications, representing the second leading cause of optic nerve-related blindness in adults
Plasma concentrations decline with age a frequently cited observation in the secondary literature, although the original quantitative data come from a small set of analyses summarized in Pickarts reviews rather than from large independent surveys (Pickart & Margolina, 2018)
