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Telomeres shorten at a rate of 2040 bases every year, and as people get older, they accumulate a high number of senescent cells, which adds to the ageing process (Starkweather et al., 2014
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The addition of diamide oxidizes GSH to GS-SG, thereby stimulating the activity of GSR to reduce GS-SG back to GSH in a NADPH-dependent manner
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