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Pathophysiology: The Underlying Immune Dysfunction Eczema arises from a combination of epidermal barrier dysfunction and immune dysregulation

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Both sleep length and quality are influenced by endocrine factors such as somatoliberin (growth hormone-releasing hormone),7 which contributes to slow-wave sleep8 an indicator of healthy slumber.9 Some research suggests, though not conclusively, that DSIP can stimulate somatoliberin secretion,10 thereby promoting the onset of a deep stage of sleep