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In addition, we found that Th1 frequency was negatively correlated with the level of HBeAg ( p =0.045, r=-0.442), and IL-17 was positively correlated with the level of ALT ( p =0.043, r=0.647)

The study protocol was approved by the ethics committee of Louisiana State Health Sciences Center-Animal Care Committee (Animal Care protocol number P-15-006), and all the methods were carried out following the approved guidelines

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Serine hydroxymethyltransferase 2 predicts unfavorable outcomes in multiple cancer: a systematic review and meta-analysis