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Resveratrol is the compound in red wine that has been demonstrated to improve heart health
Histone deacetylases including SIRT1, interact with STAT3 and negatively regulate its transcriptional activity by deacetylating critical lysine residues (Nie et al., 2009)
While it appears to be well-tolerated for treatment cycles lasting several weeks to months, the effects of continuous, prolonged use are not yet known
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